LIVE TULAREMIA VACCINE I

Identification of a Live Attenuated Vaccine Candidate for Tularemia Prophylaxis

Francisella tularensis is the causative agent of a fatal human disease, tularemia. F. tularensis was used in bioweapon programs in the past and is now classified as a category A select agent owing to its possible use in bioterror attacks. Despite over a century since its discovery, an effective vaccine is yet to be developed. In this study four transposon insertion mutants of F. tularensis live...

Aerogenic immunization of man with live Tularemia vaccine.

LIVE TULAREMIA VACCINE I. : Host-Parasite Relationship in Monkeys Vaccinated Intracutaneously or Aerogenically.

Eigelsbach, H. T. (Fort Detrick, Frederick, Md.), J. J. Tulis, M. H. McGavran and J. D. White. Live tularemia vaccine. I. Host-parasite relationship in monkeys vaccinated intracutaneously or aerogenically. J. Bacteriol. 84:1020-1027. 1962.-Bacteriological, histological, immunohistochemical, and serological studies were made on monkeys administered live tularemia vaccine strain LVS by either of ...

Modelling the impact of a live vaccine for Tularemia

Tularemia is an infectious disease caused by the bacteria Francisella tularensis. The disease is naturally occurring the the wild and primarily carried by animals and arthropods, but can also infect humans. Vectors include ticks, deer flies, horse flies and mosquitoes. A live attentuated vaccine has been available for decades, but has only received limited distribution to high-risk individuals....

[The use of tularemia live vaccine in clinical oncology].

ne of the methods of the active nonspecific antitumor immunity stimulation of cancer patients is application of bacterial antigens, from which in the past BCG vaccine was the most widely adopted (1). However, this vaccine has rather variable and short-term effects (2) that need the revaccination, whereas multiple applications of the vaccine undesirably increases the activity of suppressors and ...